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PYtest is a urea breath test and is a quantitative and non-invasive method for the diagnosis of H.pylori. The test is conducted with the patient swallowing a urea capsule. If gastric urease from H.pylori is present, the urea is split to form carbon dioxide and ammonia. Ten minutes after the capsule is ingested by the patient, a breath sample is collected in a balloon. The breath sample is transferred into collection fluid to trap the labelled carbon dioxide. This liquid is later analysed in a liquid scintillation counter to determine the level of infection.
For more information on the product, please see the TGA approved Product Information.Download Product Information Download Consumer Medicine Information
The CLOtest Rapid Urease Test (RUT) accurately and conveniently detects the urease enzyme of Helicobacter pylori in gastric mucosal biopsies. Its use is intended for the presumptive diagnosis of H.pylori infection.
CLOtest* is a well of urease indicator gel sealed inside a plastic slide. The gel contains urea, USP (29 mg/mL) phenol red (a pH indicator), buffers and a bacteriostatic agent to prevent the growth of contaminating urease-positive organisms. If the urease from H.pylori is present in the tissue sample, it changes the gel from yellow to bright magenta.Download Product Information
Treatment of Helicobacter pylori *
Antibiotic treatment and eradication of the gastric pathogen H.pylori is complex, involving multiple antibiotics that are combined with proton pump inhibitors (PPI) to increase the pH of the stomach for the duration of the course of the antibiotics to ensure high eradication rates.
Treatment failure is generally attributed to the lack of compliance with the drug regimen or infection by antibiotic resistant strains.
This study reports the antibiotic resistance of H.pylori in referred patients, reviews the necessity of pre-antibiotic sensitivity testing and ascertains the effectiveness of rifabutin (RFB),ciprofloxacin (CIP), bismuth subcitrate (BIS), furazolidone (FZD) and tetracycline (TET), in patients who have failed the standard triple therapy with PPI plus amoxicillin (AMX), clarithromycin (CLR) and/or metronidazole (MTZ).
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* Excert from: Tay CY, Windsor HM, Thirriot F, Lu W, Conway C, Perkins TT, Marshall BJ. Helicobacter pylori eradication in Western Australia using novel quadruple therapy combinations. Aliment Pharmacol Ther. 2012 Dec;36(11-12):1076-83. doi: 10.1111/apt.12089. Epub 2012 Oct 16. PMID: 23072648.
Microlit BEATUS Bottle Top Dispenser
MICROLIT BEATUS is a Bottle Top Dispenser (BTD) that offers a sophisticated blend of features and functionality. It uses Springless Valve®, an award winning technology, and Recirculation Valve for preventing loss of reagent during purging.
MICROLIT BEATUS also features two product innovations: EasyKnob® and FlexiNozzle® that enhance its ease of use and flexibility. Designed with ergonomics and intuitive handling in mind, it exhibits excellent chemical compatibility and helps in achieving precision with reliability in practical laboratory environments
Tri-Med offers these dispensers in a 5mL and 10mL volume range.
For further technical information please refer to the product catalogue.